Dihydromyricetin hmoov

Dihydromyricetin hmoov(DHM los yog DMY) yog ib tug extract ntawm vine tshuaj yej, ib tug txiv hmab txiv ntoo nroj tsuag.Nws muaj ntau yam kev lom zem zog, xws li tshem tawm dawb radicals nyob rau hauv lub cev, anti-oxidation, anti-hypertension, anti-thrombus, anti-tumor, anti-inflammatory thiab lwm yam tshwj xeeb los.

Kintai yog lub chaw tsim khoom loj ntawm dihydromyricetin, feem ntau ua tau 98% thiab 30% dej-soluble dihydromyricetin (lwm cov lus qhia tshwj xeeb tuaj yeem kho tau). Lub Hoobkas ncaj qha tsim thiab ua lag luam, nrog tus nqi pheej yig, thiab GMP, ISO, HALAL, HACCP thiab lwm yam ntawv pov thawj. Los ntawm kev txiav tawm thiab kev ua kom huv huv, peb muab cov khoom lag luam qib tshuaj, tswj dihydromyricetin hauv nws lub xeev bioactive dej-soluble tshaj plaws. Qhov no ua kom pom qhov nqus tau zoo thiab ua haujlwm tau zoo thoob plaws ntau yam kev siv. Peb cov kev tswj xyuas nruj nruj tau lees paub qhov sib xws hauv purity thiab potency, ua rau peb Dihydromyricetin hmoov ib qho kev xaiv txhim khu kev qha rau kev lag luam nrhiav cov khoom xyaw ntuj zoo. Txawm hais tias siv rau hauv cov dej haus, kev noj haus, tshuaj, lossis kev kho tawv nqaij, peb cov khoom lag luam zoo tshaj dej solubility thiab bioavailability txhawb kev txhim kho cov txheej txheem saum toj kawg nkaus.Yog tias koj xav tau kev txiav txim, thov koj xav tiv tauj peb. hu rau peb ntawm health@kintaibio.com.

High Potency & Clinical Efficacy
Kintai's Dihydromyricetin (CAS: 27200-12-0) muab tshuaj-qib purity (≥98% los ntawm HPLC), txhim kho nrog dej-soluble thev naus laus zis rau kev pom zoo bioavailability. Clinically validated rau:

• Robust hepatoprotection (ALP / AST txo los ntawm ≥35% hauv kev tshawb fawb ua ntej).
• Kev txhawb nqa plawv los ntawm cov txheej txheem antioxidant (ORAC tus nqi ≥5,000 μmol TE / g).
• Cawv metabolism acceleration (acetaldehyde clearance ↑200% vs. placebo).
• 500% solubility ntau dua li tus qauv dihydromyricetin (≥50g / L hauv dej).

Kev siv ntau yam kev lag luam

• Cov Khoom Noj Uas Muaj Cov Khoom Noj: Cov tshuaj kho mob hangover (200–500mg / capsule) thiab cov dej haus rau lub siab (0.2–1g / L).
• Pharmaceuticals: Oral formulations for the liver protection (300–600mg/day) and anti-inflammatory creams (1–3%).
• Dej haus: Cov dej haus uas tsis yog-alcoholic detox (0.5-1.5g / L) thiab txhaj tshuaj tiv thaiv kab mob.
• Tshuaj pleev ib ce: Anti-aging cream (1-5%) thiab UV-tiv thaiv serums.

Kev Tswj Xyuas Zoo

• Purity Assurance: HPLC-xyuas ≥98% purity, nrog hnyav hlau (Pb≤1ppm, As≤0.5ppm) thiab microbial txwv (≤100CFU/g).
• Stability: Dej-soluble crystalline daim ntawv ruaj khov rau 36 lub hlis (25 ℃ / 60% RH).
• Kev Ua Tau Zoo: Ua nyob rau hauv FDA-sau npe, GMP-certified chaw nrog ISO 22000 / HACCP ua raws.

Spec. & Daim ntawv xeem

                                                                               Specification ntawm DHM HPLC REPORT

                                                       Daim ntawv qhia thib peb rau DHM hnyav hlau Mycotoxins kuaj daim ntawv qhia los ntawm PONY-98% DHM

Dej Solubility ntawm peb DHM hmoov

Qhov siab tshaj plaws solubility yog: 335ml dej tuaj yeem yaj 500mg DHM hauv 60-70 ℃. Nws muaj zoo solubility nyob rau hauv dej kub, yuav luag tag nrho yaj ntawm 75 ° C, thiab tsis muaj crystals precipitate tawm thaum kub poob mus rau hauv chav tsev kub.

I. Raw Material Selection thiab Pretreatment

Raw Material Sourcing

Peb siv cov nplooj me me ntawm Ampelopsis grossedentata (vine tshuaj yej) khaws ib ncig ntawm Qingming Festival. Cov nplooj me no muaj 20-30% DMY ntau dua piv rau cov nplooj paub tab. Tag nrho cov ntaub ntawv raw tau raug soj ntsuam nruj rau cov tshuaj tua kab thiab cov hlau hnyav, kom ua tau raws li Suav Pharmacopoeia cov qauv.

Txheej txheem Pretreatment

• Kev ziab sai: Cov nplooj qhuav qhuav ntawm 60 ° C siv cua kub ncig kom txog thaum cov ntsiab lus noo noo qis dua 8%, khaws cov khoom xyaw nquag.
• Sib tsoo thiab tshuaj ntsuam: Cov nplooj qhuav yog av thiab tshuaj xyuas los ntawm 40-mesh sieve. Qhov no tsub kom qhov chaw nto, txhim khu kev extraction efficiency.

II. Core Extraction Technologies

Microwave-Ethanol Synergistic Extraction (Cov txheej txheem Patented)

• Qhov hnyav piv: Peb siv 60% cov zaub mov-qib ethanol tov nrog cov kua-kua piv ntawm 1:15 (g / mL).
• Microwave Pab: Ntawm 500W lub zog, 50 feeb ntawm hluav taws xob, thiab 60 ° C, cov nqi rho tawm ntau dua 90%.
• Kev txuag hluav taws xob: Lub kaw lus kaw lub kaw lus rov ua dua ethanol, txo qis qis dua 5%.

Optimized Dej Extraction (Kev Xaiv Tus Nqi Tsawg)

• Pure Dej Extraction: Siv 1:20 khoom-kua piv, boiling ntawm 80 ° C rau 2 teev ua tiav 85% rho tawm tus nqi.
• Dynamic Countercurrent Extraction: Peb-theem tandem extraction tso tsheb hlau luam txo cov kev siv hnyav los ntawm 30%.

III. Purification thiab Refinement

Kev Ua Haujlwm Tseem Ceeb

• Vacuum Concentration: Extracts yog concentrated ntawm 40 ° C nyob rau hauv lub tshuab nqus tsev vacuum. Cov dej khib nyiab nrog BOD <100 nkag mus rau peb qhov kev kho mob.
• pH Precipitation: Ntxiv dej txias (pH = 6) precipitates impurities, ua raws li decolorization nrog activated carbon.

Advanced Purification

• Macroporous Resin Chromatography: AB-8 resin nrog ethanol gradient elution boosts purity mus rau 95%.
• Low-Temperature Recrystallization: Ob lub voj voog recrystallization nyob rau hauv 4: 1 ethanol-dej system yield khoom nrog ≥98% purity thiab 75% rov qab.

IV. Quality Control thiab Innovation

Kev soj ntsuam online

HPLC tsis tu ncua saib xyuas DMY cov ntsiab lus, ua kom cov khoom sib xws (RSD<2%).

Derivative Product Development

• Esterification: Reacting DMY nrog linoleic acid tsim DMY linoleate, txhim kho lipid solubility thiab antioxidant zog.
• Water-Soluble Formulation: Kev sib xyaw nrog PVP K30 ua rau DMY dej-soluble, nthuav dav siv hauv tshuaj pleev ib ce.

1. Antioxidant: Nrog rau qhov nce ntawm purity ntawm dihydromyricetin, cov nyhuv antioxidant yog txhim kho, uas tuaj yeem tshem tawm cov dawb radicals hauv lub cev, txo qhov kev puas tsuaj los ntawm cov dawb radicals rau cov hlwb thiab cov ntaub so ntswg, yog li ncua kev laus, thiab muaj zog antioxidant nyhuv rau tsiaj. roj thiab zaub roj.

2. Tiv thaiv daim siab: Dihydromyricetin tuaj yeem txhawb kev decomposition ntawm ethanol metabolites, ua lub luag haujlwm tiv thaiv kev haus dej cawv thiab haus cawv, txo cawv ua rau lub siab, txhim kho daim siab cell puas, inhibit daim siab cell deterioration, thiab ua lub luag haujlwm tiv thaiv daim siab.

3.Antibacterial nyhuv: Cov kev sim tau pom tias dihydromyricetin muaj cov kab mob tua kab mob ntawm Bacillus subtilis, Staphylococcus aureus, salmonella thiab lwm yam kab mob, thiab cov tshuaj tua kab mob muaj zog tshaj plaws hauv pH3 ~ 4 ib puag ncig, tab sis cov nyhuv inhibitory ntawm fungi tsis pom tseeb.4. Cov teebmeem Antitumor: Cov kev tshawb fawb tau pom tias dihydromycetin muaj peev xwm los txhim kho qog noj ntshav thiab txhim kho cov tsos mob tseem ceeb ntawm tus neeg mob los ntawm inhibiting qog angiogenesis thiab modulating thiab txhim kho kev tiv thaiv kab mob ntawm tes. Hauv kev sim cov kev tshawb fawb ntawm cov qog ua qauv xws li leukemia thiab nasopharyngeal carcinoma, nws tau pom tias muaj kev tiv thaiv qog nqaij hlav, uas muab lub tswv yim tshiab thiab kev cia siab rau kev kho mob qog.

Tam sim no, dihydromyricetin feem ntau yog siv los ua cov khoom kho mob, tab sis kuj tseem tuaj yeem siv rau hauv kev kho mob ntawm cov kab mob ua pa, haus dej cawv ntawm Suav patent tshuaj npaj, xws li ntsiav tshuaj, tshuaj ntsiav, thiab granules.

1. Cov dej haus thiab cov khoom siv ntxiv

Vim nws lub siab - tiv thaiv thiab tiv thaiv hangover zog,Dihydromyricetin hmoov yog ib qho khoom siv nrov hauv cov dej haus ua haujlwm. Nws tuaj yeem muab ntxiv rau cov dej haus ntawm qhov siab ntawm 0.2 - 1g / L, muab cov neeg siv khoom yooj yim los tiv thaiv lawv daim siab tom qab haus cawv. Hauv kev noj zaub mov noj, nws feem ntau yog tsim rau hauv cov tshuaj ntsiav lossis ntsiav tshuaj, nrog rau kev noj tshuaj ntawm 200 - 500mg rau ib qho kev pabcuam, tsom rau cov neeg paub txog kev noj qab haus huv nrhiav kev txhim kho lawv lub siab tag nrho thiab kev noj qab haus huv hauv metabolic.

2. Kev lag luam kws tshuaj

Hauv kev lag luam tshuaj, DHM qhia tau zoo heev. Nws cov tshuaj tua kab mob antioxidant thiab tshuaj tiv thaiv kab mob ua rau nws muaj txiaj ntsig zoo hauv cov tshuaj kho mob siab. Nws tuaj yeem tsim los rau hauv cov qauv hauv qhov ncauj, nrog kev noj txhua hnub ntawm 300 - 600mg, los pab kho lub siab hlwb thiab txhim kho daim siab ua haujlwm. Tsis tas li ntawd, nws cov khoom tiv thaiv neuroprotective tuaj yeem pab txhawb kev tsim cov tshuaj rau cov kab mob neurodegenerative, txawm hais tias kev tshawb fawb ntxiv tseem tab tom ua.

3. Cosmetics Field

Lub peev xwm antioxidant zoo heev ntawm Dihydromyricetin ua rau nws tawm tsam dawb radicals, ua rau nws tsim nyog rau cov tshuaj pleev ib ce los tiv thaiv kev laus. Nws tuaj yeem muab ntxiv rau cov tshuaj nplaum, cov tshuaj pleev xim, thiab cov tshuaj pleev ib ce ntawm qhov ntau ntawm 1 - 5%. Nws pab txo cov tsos ntawm wrinkles, txhim kho daim tawv nqaij kev ntxhib los mos, thiab tiv thaiv daim tawv nqaij los ntawm ib puag ncig puas. Tsis tas li ntawd, nws cov khoom tiv thaiv kab mob tuaj yeem ua tau zoo rau cov khoom tu tawv nqaij rhiab heev, soothing khaus ntawm daim tawv nqaij thiab txo qhov liab.

4. Kev lag luam zaub mov ua Antioxidant

Raws li lub ntuj antioxidant, DHM tuaj yeem siv rau hauv kev lag luam khoom noj kom ntev lub neej ntawm cov khoom noj khoom haus. Nws tuaj yeem muab ntxiv rau cov roj noj, cov nqaij ua tiav, thiab khoom noj txom ncauj. Piv txwv li, nyob rau hauv cov roj edible, ntxiv me me (0.01 - 0.05%) tuaj yeem cuam tshuam lipid oxidation, tswj cov roj zoo thiab tsw, thaum tseem muab cov neeg siv khoom noj khoom haus ntxiv.

5. Tsiaj Pub Ntxiv

Hauv kev ua liaj ua teb, Dihydromyricetin tuaj yeem siv los ua khoom noj rau tsiaj txhu. Nrog rau qib ntxiv ntawm 10 - 20mg / kg hauv cov tsiaj pub, nws tuaj yeem txhim kho cov tsiaj tiv thaiv kab mob, txhim kho lawv txoj kev loj hlob, thiab txo qhov tshwm sim ntawm cov kab mob. Qhov no tsis yog tsuas yog pab tsiaj noj qab haus huv xwb tab sis kuj muaj kev cuam tshuam zoo rau qhov zoo thiab kev nyab xeeb ntawm cov khoom siv tsiaj.

Toxicological kev txiav txim siab

KINTAI's Dihydromyricetin hmoov qhia tau tias mob toxicity tsawg. Cov kev tshawb fawb tsiaj tau qhia tias qhov ncauj LD₅₀ tus nqi siab tshaj 2000 mg / kg, qhia tias muaj kev pheej hmoo tsis zoo ntawm kev mob hnyav ntawm kev siv ib txwm. Tsis muaj qhov cuam tshuam loj heev tau raug tshaj tawm hauv tib neeg daim ntawv thov nyob rau hauv qhov pom zoo ntau npaum li cas. Txawm hais tias kev kis tus kab mob mus ntev yog suav hais tias feem ntau muaj kev nyab xeeb, kev noj zaub mov tsis zoo yuav ua rau muaj cov tsos mob me xws li plab zom mov lossis xeev siab hauv qee tus neeg mob. Txhawm rau tiv thaiv cov neeg siv khoom zoo, KINTAI tsis tu ncua ua cov tshuaj toxicity tag nrho, ua kom muaj kev ua raws li cov cai tswj kev nyab xeeb.

Kev Tswj Xyuas Zoo & Kev Nyab Xeeb Kev Nyab Xeeb

Tsim nyob rau hauv cov chaw uas ua tau raws li Kev Tswj Xyuas Zoo (GMP) cov qauv, KINTAI's DMY tsis tu ncua tswj hwm qib purity ntawm ≥98%, raws li kev txheeb xyuas tseeb los ntawm High - Performance Liquid Chromatography (HPLC). Txhua batch raug soj ntsuam nruj me ntsis rau cov hlau hnyav, nrog rau kev txwv ntawm Pb ≤2ppm thiab As ≤1ppm. Tsis tas li ntawd, cov kuab tshuaj residual thiab microbial kev nyab xeeb raug tshuaj xyuas nruj. Daim Ntawv Pov Thawj Paub Txog Kev Ntsuam Xyuas (COA) thiab Cov Ntaub Ntawv Kev Nyab Xeeb Cov Ntaub Ntawv (MSDS) tau muab rau txhua pawg, lees paub ua raws li kev nyab xeeb thoob ntiaj teb cov qauv tsim los ntawm FDA, EFSA, thiab WHO.

Kev ceeb toom kev nyab xeeb & txwv

• Cov Tshuaj Tiv Thaiv: Vim cov ntaub ntawv kev nyab xeeb tsis txaus, Dihydromyricetin hmoov tsis pom zoo rau cov poj niam cev xeeb tub lossis lactating yam tsis muaj kev sab laj kho mob ua ntej.
• Kev Tsis Pom Zoo: Kev noj ntau dhau yuav ua rau mob plab me ntsis. Yog hais tias muaj kev tsis xis nyob los yog tshwm sim tsis zoo tshwm sim, tam sim ntawd txiav kev siv tam sim ntawd.
• Kev tuav haujlwm: Txhawm rau kom tsis txhob muaj qhov ua pa ua pa, kev nqus tau ncaj qha ntawm cov hmoov yuav tsum tau zam nruj me ntsis. Nws raug nquahu kom tuav cov hmoov hauv qhov chaw zoo-ventilated. Khaws cov khoom nyob rau hauv qhov chaw txias, qhuav, tiv thaiv los ntawm tshav ntuj ncaj qha los tswj nws qhov zoo thiab ruaj khov.

1. Peb cog lus tias peb cov ntaub ntawv raw yog ib txwm loj hlob tsis muaj additives.
2. Peb muab cov kev daws teeb meem tshwj xeeb los tsim Dihydromyricetin.
3. Peb cov chaw tsim khoom tuav cov ntawv pov thawj thoob ntiaj teb suav nrog GMP, ISO 9001, ISO 22000, HACCP, KOSHER, thiab HALAL.

Q1: Dab tsi yog lwm lub npe rau dihydromyricetin?

A1: Ampelopsin, tseem hu ua dihydromyricetin thiab DHM, thaum siv los ua tshuaj ntsuab, yog flavanonol, hom flavonoid.

Q2: Puas yog DMY pab nrog hangover?

A2: Nws yog lub npe hu rau ntau pua xyoo hauv cov tshuaj suav tshuaj suav tshuaj raws li kev kho rau cawv lom thiab hangover.